Synthesized Pyrazoline-Carbothioamide as Potent Antitubercular Agent

Synthesized Pyrazoline-Carbothioamide as Potent Antitubercular Agent

» 24.09.2017 06:35

Synthesized Pyrazoline-Carbothioamide as Potent Antitubercular Agent


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Ebook Details:

Author: Dhrubo Jyoti Sen
ISBN: 9783659142932
A brief introduction of M.tuberculosis has been summarized. Pharmacological importance and literature survey of pyrazolo derivatives has been summarized. All the synthesized compounds were characterized by UV, IR, Mass and 1H-NMRspectroscopy. All the newly synthesized compounds have been screened for antibacterial activity. Streptomycin was used as standard reference drug. Compound 57b has been found to have better antibacterial activity against gram+ve bacteria S.aureus and B.subtilis as compared to other synthesized compounds. Compounds 57b, 58a, 58b have been found to have better activity against gram-ve bacteria. None of the compound has been found to be equipotent with standard streptomycin. All the newly synthesized compounds were screened for antitubercular activity. Compound 57b has been found to be most potent among the series having MIC 6.25 µg/ml. Others synthesised compounds have been found to be active (having MIC 57a: 500 µg/ml, 57c: 25 µg/ml, 58a: 25 µg/ml, 58b: 62.5 µg/ml, 58c: 250 µg/ml). None of the compound has been found to be equipotent with standard isoniazid.

Title: Synthesized Pyrazoline-Carbothioamide as ...

Publisher: LAP Lambert Academic Publishing

Binding: Paperback

Book Condition:New

Book Type: Paperback




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Synthesized Pyrazoline-Carbothioamide as Potent Antitubercular Agent EPUB

» 26.09.2017 12:40

Thanks ALMIGHTY, great giveaway!!
Yeah, Quirrell was a great teacher. There was just that minor drawback of him having Lord Voldemort sticking out of the back of his head!
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